Free shipping over $200

KLOW

$149.99

≥99% Purity · COA
KLOW research peptide vial

Research-Grade Compound · RUO

KLOW Research Blend 80mg (GHK-Cu · KPV · BPC-157 · TB-500)

Pre-blended 80mg four-peptide dermal and connective tissue research panel — GHK-Cu 50mg, KPV 10mg, BPC-157 10mg and TB-500 10mg — studied for extracellular matrix remodeling, melanocortin receptor signaling, actin cytoskeletal dynamics, and growth factor pathway biology in coordinated in-vitro multi-analyte assay systems

$149.99

80 mgUSD · Research Grade

GHK-Cu 50mg · KPV 10mg · BPC-157 10mg · TB-500 10mg

In stock — ships same or next business day from the United States

Quantity
1

Lyophilized, filled and sealed in our U.S. facility from globally sourced peptide. Independently third-party tested, with batch-specific COAs on file.

≥99% Purity VerifiedSecure CheckoutPlain Professional PackagingShips Same or Next Business Day · U.S. Domestic

Purity Guarantee

If any compound falls short of ≥99% purity on its COA, contact us and we'll make it right.

Add $200.00 more for free shipping. Keep Shopping

⚗ Research Use Only. Not for human consumption.

Scientific Context

Research Applications

  • 01

    Dermatological researchers investigating coordinated four-peptide effects on collagen biosynthesis, elastin gene expression, and extracellular matrix remodeling in human fibroblast and keratinocyte co-culture models

  • 02

    Cell biology laboratories examining compound synergy across melanocortin receptor (MC1R/MC3R) signaling, actin cytoskeletal dynamics, and growth factor pathway engagement within a single in-vitro system

  • 03

    Scientists studying copper-dependent enzymatic activity (GHK-Cu), melanocortin-mediated NF-κB pathway modulation (KPV), actin-mediated cellular migration biology (TB-500), and fibroblast proliferation signaling (BPC-157) as a coordinated multi-pathway in-vitro research panel

Observed Mechanisms

In-Vitro Activity Profile

01

GHK-Cu 50mg: Copper-Mediated Matrix Remodeling

The tripeptide-copper complex GHK-Cu has been studied in vitro for copper ion transport into dermal fibroblasts, engaging copper-dependent enzymatic pathways and upregulating collagen I, III, and elastin gene expression — providing the extracellular matrix remodeling arm of the panel.

02

KPV 10mg: Melanocortin Receptor & NF-κB Pathway

KPV, the C-terminal tripeptide of α-MSH, has been studied for binding affinity at MC1R and MC3R subtypes with downstream effects on cAMP signaling and NF-κB pathway modulation, contributing the melanocortin receptor and anti-inflammatory signaling dimension to the combined panel.

03

TB-500 10mg: Actin Dynamics & Cellular Migration

TB-500 binds monomeric G-actin through its LKKTET motif, modulating cytoskeletal reorganization and cellular motility in scratch assay models — contributing the cellular migration and angiogenic signaling dimension of the combined panel.

04

BPC-157 10mg: Growth Factor & Fibroblast Activity

BPC-157 contributes growth factor receptor pathway engagement and fibroblast proliferation signaling to the panel, with preclinical studies documenting associations with epithelial cell proliferation markers and collagen synthesis rate changes in connective tissue culture systems.

Related Compounds

Frequently Researched Together

KLOW is a single pre-blended 80mg vial combining GHK-Cu (50mg), KPV (10mg), BPC-157 (10mg) and TB-500 (10mg) — extending the three-peptide GLOW dermal panel with KPV, the C-terminal alpha-MSH tripeptide, which adds melanocortin receptor and NF-kB pathway coverage to the extracellular matrix remodeling (GHK-Cu), actin cytoskeletal (TB-500) and growth factor pathway (BPC-157) arms.

Common Questions

FAQ

AVERA

Refined Wellness

A curated research collection designed for scientific exploration and advanced laboratory study.

Fulfilled from the United States · Domestic dispatch only

support@averarefined.com

📍67 Newtown Road, Danbury CT 06810

⚗ For In-Vitro Laboratory Research Use Only

All compounds are strictly for qualified research professionals. Not for human consumption, veterinary use, or clinical procedures.

All products sold by Avera Refined Wellness are intended strictly for in-vitro laboratory research purposes only. Not for human consumption, veterinary use, or clinical/diagnostic procedures. These products are not drugs, supplements, or medical devices and have not been evaluated or approved by the FDA, DEA, or any other regulatory authority to diagnose, treat, cure, or prevent any disease or condition. Purchasers are solely responsible for compliance with all applicable federal, state, and local laws. By purchasing, you confirm you are a qualified research professional aged 21 or older.

© 2026 Avera Refined Wellness. All rights reserved.