TB-500
$54.99
Research-Grade Compound · RUO
TB-500 Research Peptide
Synthetic analogue of the Thymosin Beta-4 C-terminal actin-binding domain, studied for cellular migration dynamics and angiogenic signaling in vitro
Kit Available — Save up to 25%
Research Kit — available in 5 or 10 vials · from $410.00
For extended or multi-replicate research protocols. For in-vitro laboratory research use only.
$54.99
10 mgUSD · Research GradeIn stock — ships same or next business day from the United States
Lyophilized, filled and sealed in our U.S. facility from globally sourced peptide. Independently third-party tested, with batch-specific COAs on file.
Purity Guarantee
If any compound falls short of ≥99% purity on its COA, contact us and we'll make it right.
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⚗ Research Use Only. Not for human consumption.
Scientific Context
Research Applications
- 01
Cell biology researchers investigating actin cytoskeletal dynamics and cellular motility mechanisms in in-vitro wound model assays
- 02
Vascular biology laboratories studying tubulogenesis and angiogenic factor expression under experimental conditions
- 03
Scientists examining anti-inflammatory peptide signaling in tissue culture models of acute injury response
Observed Mechanisms
In-Vitro Activity Profile
G-Actin Sequestration
Binds monomeric G-actin through its LKKTET motif, modulating the G-actin:F-actin ratio and influencing cytoskeletal reorganization associated with cell migration in scratch assay models.
Angiogenic Factor Expression
In-vitro and preclinical studies have examined its association with VEGF expression and endothelial tube formation in cell culture systems modeling vascular biology.
Inflammatory Mediator Regulation
Laboratory models have documented alterations in select inflammatory mediator profiles following TB-500 exposure, suggesting potential utility in inflammatory signaling research.
Related Compounds
Frequently Researched Together
TB-500 is a synthetic peptide corresponding to the active region of Thymosin Beta-4 (Tβ4), a highly conserved 43-amino acid protein involved in actin sequestration and cytoskeletal regulation. Research has investigated its role in promoting cell migration, proliferation, and differentiation in tissue culture models. Studies have explored its interactions with G-actin and potential implications in wound healing biology, angiogenesis research, and inflammatory signaling cascades. All research is conducted in in-vitro laboratory settings.
Common Questions